• 연구실 : 원천관 205호
• 연구실 전화 : 2548
• 이메일 : hurji@ajou.ac.kr
• 연구관심분야 : Neuroscience, Alzheimer's disease
• 홈페이지 :

• 2010.05 Karolinska Inst Stockholm 박사

2022 – 현재  아주대학교 조교수
2019 – 2022  Memorial Sloan Kettering Cancer Center, Senior Research Scientist
2016 – 2019  Memorial Sloan Kettering Cancer Center, Research Associate
2011 – 2016  Memorial Sloan Kettering Cancer Center, Research Fellow
2010 – 2011  Karolinska Institutet, Postdoctoral Fellow

1. [논문] 저자 허지연, 제목Gamma-secretase in Alzheimers dissease 저널 , EXPERIMENTAL AND MOLECULAR MEDICINE 볼륨 , Vol.54 번호 , No.4 페이지 , pp.433 -446 (Apr, 2022)
2. [논문] 저자 허지연, 제목Innate immunity protein IFITM3 in Alzheimer’s disease. 저널 , DNA AND CELL BIOLOGY 볼륨 번호 페이지 , pp.1351 -1355 (Nov, 2021)
3. [논문] 저자 허지연, Georgia R. Frost, Alan E. Renton, Alison Goate, Andrew McKenzie, Bianca T. Esposito, Bin Zhang, Chen Ming, Christina Crump, Douglas S. Johnson, Eitan Wong, Eliezer Masliah, Ivy Trinh, Jen Chyong Wang, Julia TCW, Ketherine R. Sadleir, Lei Guo, Marilia Barros, Minghui Wang, Paul Greengard, Pengju Nie, Robert A. Rissman, Robert Vassar, Si Jia Pan, Thomas Li, Xianxiao Zhou, Xianzhong Wu, Yong Kim, Yotam Sagi, Yujia Zhai, Yue-Ming Li, 제목The innate immunity protein IFITM3 modulates gamma-secretase in Alzheimer’s disease. 저널 , Nature 볼륨 , Vol.586 번호 , No.7831 페이지 , pp.735 -740 (Oct, 2020)
4. [논문] 저자 Mitsuhiro Inoue, 허지연, Bengt Winblad, Birgitta Wiehager, Lars O. Tjernberg, Natsuko G Yamamoto, Taizo Ishikawa, Takahiro Kihara, Yasuhiro Teranishi , Sophia Schedin-Weiss, 제목Human brain proteins showing neuron-specific interactions with gamma-secretase. 저널 , FEBS Journal 볼륨 , Vol.282 번호 , No.14 페이지 , pp.2587 -2599 (Apr, 2015)
5. [논문] 저자 허지연, A Dedeoglu, H Li, H Li, H Zheng, H Zhu, I Carreras, M Mwamburi, M Wallack, N Kowall, R Fine, RA Stern, X Sun, X Wang, WQ Qiu, 제목Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease. 저널 , Molecular Psychiatry 볼륨 , Vol.20 번호 , No.2 페이지 , pp.252 -262 (Feb, 2015)

1. [논문] 저자 허지연, 제목Gamma-secretase in Alzheimers dissease 저널 , EXPERIMENTAL AND MOLECULAR MEDICINE 볼륨 , Vol.54 번호 , No.4 페이지 , pp.433 -446 (Apr, 2022)
2. [논문] 저자 허지연, 제목Innate immunity protein IFITM3 in Alzheimer’s disease. 저널 , DNA AND CELL BIOLOGY 볼륨 번호 페이지 , pp.1351 -1355 (Nov, 2021)
3. [논문] 저자 허지연, Georgia R. Frost, Alan E. Renton, Alison Goate, Andrew McKenzie, Bianca T. Esposito, Bin Zhang, Chen Ming, Christina Crump, Douglas S. Johnson, Eitan Wong, Eliezer Masliah, Ivy Trinh, Jen Chyong Wang, Julia TCW, Ketherine R. Sadleir, Lei Guo, Marilia Barros, Minghui Wang, Paul Greengard, Pengju Nie, Robert A. Rissman, Robert Vassar, Si Jia Pan, Thomas Li, Xianxiao Zhou, Xianzhong Wu, Yong Kim, Yotam Sagi, Yujia Zhai, Yue-Ming Li, 제목The innate immunity protein IFITM3 modulates gamma-secretase in Alzheimer’s disease. 저널 , Nature 볼륨 , Vol.586 번호 , No.7831 페이지 , pp.735 -740 (Oct, 2020)
4. [논문] 저자 Mitsuhiro Inoue, 허지연, Bengt Winblad, Birgitta Wiehager, Lars O. Tjernberg, Natsuko G Yamamoto, Taizo Ishikawa, Takahiro Kihara, Yasuhiro Teranishi , Sophia Schedin-Weiss, 제목Human brain proteins showing neuron-specific interactions with gamma-secretase. 저널 , FEBS Journal 볼륨 , Vol.282 번호 , No.14 페이지 , pp.2587 -2599 (Apr, 2015)
5. [논문] 저자 허지연, A Dedeoglu, H Li, H Li, H Zheng, H Zhu, I Carreras, M Mwamburi, M Wallack, N Kowall, R Fine, RA Stern, X Sun, X Wang, WQ Qiu, 제목Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease. 저널 , Molecular Psychiatry 볼륨 , Vol.20 번호 , No.2 페이지 , pp.252 -262 (Feb, 2015)
6. [논문] 저자 Hongmei Li, Qinxi Guo, 허지연, Allysa L. Cole, Yueming Li, H Zheng, 제목Modeling Alzheimer’s disease in mouse without mutant protein overexpression: Cooperative and independent effects of Aβ and Tau. 저널 , PLoS ONE 볼륨 , Vol.8 번호 , No.11 페이지 , pp.e80706 -e80706 (Nov, 2013)
7. [논문] 저자 Yasuhiro Teranishi, 허지연, Bengt Winblad, Gucci Jijuan Gu, Homira Behbahani, Masood Kamali-Moghaddam, Susanne Frykman, Taizo Ishikawa, Takahiro Kihara, Takeshi Nishimura, Lars O. Tjernberg, 제목Erlin-2 is associated with active gamma-secretase in brain and affects amyloid β-peptide production. 저널 , Biochemical and Biophysical Research Communications 볼륨 , Vol.424 번호 , No.3 페이지 , pp.476 -481 (Aug, 2012)
8. [논문] 저자 허지연, Anna Sandebring, Bengt Winblad, Lars O. Tjernberg, Maria Ancarcrona, Natsuko Goto Yamamoto, Nenad Bogdanovic, Sophia Schedin-Weiss, Takahiro Kihara, Takeshi Nishimura, Yasuhiro Teranishi, Susanne Frykman, 제목Identification of two novel synaptic gamma-secretase associatd proteins that affect amyloid beta-peptide levels without altering Notch processing. 저널 , NEUROCHEMISTRY INTERNATIONAL 볼륨 , Vol.61 번호 , No.1 페이지 , pp.108 -118 (Apr, 2012)
9. [논문] 저자 Natsuko Goto Yamamoto, Bengt Winblad, Lars O Tjernberg, Masakazu Hashimoto, Mitsuhiro Inoue, Susanne Frykman, Takahiro Kihara, Waltteri Hosia, Yasuhiro Teranishi, 허지연, 제목Identification of novel gamma-secretase-associated proteins in detergent-resistant membranes from brain. 저널 , JOURNAL OF BIOLOGICAL CHEMISTRY 볼륨 , Vol.287 번호 , No.15 페이지 , pp.11991 -12005 (Apr, 2012)
10. [논문] 저자 Yasuhiro Teranishi, 허지연, Bengt Winblad, Hedvig Welander, Jenny Frånberg, Mikio Aoki, Susanne Frykman, Lars O. Tjernberg, 제목Affinity pulldown of gamma-secretase and associated proteins from human and rat brain. 저널 , Journal of Cellular and Molecular Medicine 볼륨 , Vol.14 번호 , No.11 페이지 , pp.2675 -2686 (Nov, 2010)
11. [논문] 저자 허지연, Bengt Winblad, Homira Behbahani, Jarmila Nahalkova, Jenny Frånberg, Lars O. Tjernberg, Mikio Aoki, Susanne Frykman, 제목Synaptic and endosomal localization of active gamma-secretase in rat brain. 저널 , PLoS ONE 볼륨 , Vol.5 번호 , No.1 페이지 , pp.e8948 -e8948 (Jan, 2010)
12. [논문] 저자 허지연, Bengt Winblad, Hedvig Welander, Homira Behbahani, Jenny Frånberg, Mikio Aoki, Susanne Frykman, Lars O. Tjernberg, 제목Active gamma-secretase is localized to detergent-resistantmembranes in human brain. 저널 , FEBS Journal 볼륨 , Vol.275 번호 , No.6 페이지 , pp.1174 -1187 (Mar, 2008)

1. [논문] 저자 소정온, 송미숙, 심혜진, 이필휴, 주인수, 허지연, 김영호, 김종원, 나덕렬, 박문호, 정선주, 묵인희, 제목알쯔하이머병 환자 혈청에서의 베타 아밀로이드 단백질에 대한 특이 항체량 측정: 알쯔하이머병의 생화학적 진단지표 개발 저널 , Dementia and Neurocognitive Disorders 볼륨 , Vol.3 번호 , No.1 페이지 , pp.37 -41 (Jan, 2004)

1. [학술회의] 저자 허지연, 제목The innate immunity protein IFITM3 modulates gamma-secretase in Alzheimer’s disease. 저널 , The 15th International Conference on Alzheimer’s & Parkinson’s Diseases. 볼륨 번호 페이지 (Mar, 2021)
2. [학술회의] 저자 허지연, Y. Li, A. Goate, A. McKenzie, B. Zhang, C. Crump, D. Johnson, E. Masliah, G. R. Frost, J. TCW, J. Wang, K. R. Sadleir, P. Greengard, R. Rissman, R. Vassar, S. Pan, X. Wu, Y. Sagi, 제목Innate immune system modulates gamma-secretase with aging and in Alzheimer’s disease. 저널 , Society for Neuroscience 48th Annual Meeting 볼륨 번호 페이지 (Nov, 2018)
3. [학술회의] 저자 허지연, Bengt Winblad, Hedvig Welander, Lars O. Tjernberg, Masakazu Hashimoto, Susanne Frykman, Waltteri Hosia, Yasuhiro Teranishi, 제목Gamma-Secretase associated proteins in detergent resistant membranes from brain. 저널 , 13th International Conference on Alzheimer’s Disease and Related Disorders. 볼륨 번호 페이지 (Jul, 2010)
4. [학술회의] 저자 허지연, 제목Active gamma-secretase is localized to detergent resistant membranes in human brain. 저널 , 11th International Conference on Alzheimer’s Disease and Related Disorders. 볼륨 번호 페이지 (Jul, 2008)

1. [학술회의] 저자 허지연, 제목The modulation of gamma-secretase in Alzheimer’s disease 저널 , 2022 제39차 한국노화학회 추계학술대회 볼륨 번호 페이지 (Dec, 2022)
2. [학술회의] 저자 허지연, 제목Innate immunity protein IFITM3 modulates gamma-secretase in Alzheimer’s disease. 저널 , 한국노화학회 춘계학술대회 볼륨 번호 페이지 (Jun, 2021)